George Tellides Selected Research

Arteriosclerosis

1/2014	SOCS1 prevents graft arteriosclerosis by preserving endothelial cell function.
8/2012	Molecular imaging of vascular endothelial growth factor receptors in graft arteriosclerosis.
12/2011	Activation of human vascular cells decreases their expression of transforming growth factor-beta.
8/2011	AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion.
7/2010	IFN-gamma primes intact human coronary arteries and cultured coronary smooth muscle cells to double-stranded RNA- and self-RNA-induced inflammatory responses by upregulating TLR3 and melanoma differentiation-associated gene 5.
9/2008	Amelioration of human allograft arterial injury by atorvastatin or simvastatin correlates with reduction of interferon-gamma production by infiltrating T cells.
3/2008	Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation.
9/2007	Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.
6/2007	Alloimmune-mediated vascular remodeling of human coronary artery grafts in immunodeficient mouse recipients is independent of preexisting atherosclerosis.
3/2007	Interferon-gamma axis in graft arteriosclerosis.

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George Tellides Research Topics

Disease

14	Inflammation (Inflammations) 01/2022 - 06/2005
14	Atherosclerosis 11/2021 - 11/2006
12	Arteriosclerosis 01/2014 - 03/2004
8	Pathologic Constriction (Stenosis) 04/2022 - 09/2005
8	Neointima 01/2017 - 08/2011
8	Vascular Remodeling 11/2014 - 03/2004
6	Aortic Aneurysm (Aneurysm, Aortic) 01/2022 - 01/2008
6	Aneurysm (Aneurysms) 01/2022 - 09/2005
6	Hyperplasia 01/2020 - 03/2004
6	Coronary Artery Disease (Coronary Atherosclerosis) 02/2017 - 09/2006
5	Atherosclerotic Plaque (Atheroma) 11/2021 - 01/2016
5	Thoracic Aortic Aneurysm 01/2020 - 09/2005
4	Aortic Diseases 01/2022 - 02/2014
4	Williams Syndrome (Williams-Beuren Syndrome) 01/2017 - 10/2012
3	Heart Diseases (Heart Disease) 01/2022 - 03/2009
3	Fibrosis (Cirrhosis) 01/2021 - 01/2017
3	Supravalvular Aortic Stenosis (Aortic Supravalvular Stenosis) 03/2016 - 10/2012
3	Abdominal Aortic Aneurysm 11/2014 - 08/2005
2	Hypertrophy 01/2022 - 01/2022
2	Rupture 01/2022 - 01/2022
2	Ischemia 01/2021 - 09/2013
2	Hypoxia (Hypoxemia) 01/2021 - 09/2013
2	Reperfusion Injury 11/2020 - 01/2004
2	Aortic Dissection 04/2020 - 01/2016
2	Thrombosis (Thrombus) 01/2019 - 01/2016
2	Hemorrhage 01/2019 - 01/2016
2	Cardiomyopathies (Cardiomyopathy) 11/2015 - 05/2012
2	Cardiovascular Diseases (Cardiovascular Disease) 11/2015 - 12/2012
2	Marfan Syndrome (Marfan's Syndrome) 02/2014 - 09/2012
2	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 08/2012 - 04/2006
2	Heart Failure 05/2012 - 03/2007
1	Aortic Valve Disease 04/2022
1	Familial Hypertrophic Cardiomyopathy (Cardiomyopathy, Familial Hypertrophic) 01/2022
1	Aortic Rupture 01/2022
1	False Aneurysm (Pseudoaneurysm) 01/2022
1	Arteriovenous Fistula 01/2022
1	Cardiomegaly (Heart Hypertrophy) 01/2022
1	Hematoma 01/2022
1	Disease Progression 11/2021
1	Chronic Kidney Failure (Chronic Renal Failure) 07/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021
1	Delayed Graft Function 11/2020

Drug/Important Bio-Agent (IBA)

11	InterferonsIBA 11/2021 - 03/2004
8	Proteins (Proteins, Gene)FDA Link 04/2022 - 09/2005
8	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2020 - 12/2011
8	CytokinesIBA 01/2014 - 09/2005
7	ElastinIBA 01/2022 - 10/2012
7	Phenobarbital (Luminal)FDA Link 01/2017 - 03/2004
5	Sirolimus (Rapamycin)FDA Link 01/2022 - 09/2007
5	CollagenIBA 01/2022 - 04/2008
4	Apolipoproteins E (ApoE)IBA 01/2022 - 10/2015
4	LigandsIBA 03/2016 - 03/2007
4	Interferon-gamma (Interferon, gamma)IBA 03/2012 - 03/2004
3	RNA (Ribonucleic Acid)IBA 01/2021 - 07/2010
3	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2016 - 10/2015
3	ChemokinesIBA 03/2012 - 06/2005
2	Transforming Growth Factor beta (TGF-beta)IBA 01/2022 - 01/2016
2	EnzymesIBA 11/2021 - 03/2012
2	SolutionsIBA 01/2021 - 01/2021
2	Interleukin-18 (Interleukin 18)IBA 11/2020 - 01/2007
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2019 - 01/2007
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 03/2016
2	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2019 - 01/2008
2	LipidsIBA 01/2019 - 01/2019
2	MTOR InhibitorsIBA 01/2019 - 01/2017
2	Fibronectins (Fibronectin)IBA 01/2019 - 10/2015
2	IntegrinsIBA 01/2018 - 03/2016
2	CalciumIBA 02/2017 - 05/2012
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2016 - 02/2014
2	Transforming Growth Factor-beta Type II ReceptorIBA 11/2014 - 02/2014
2	Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA 03/2014 - 11/2006
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2012 - 08/2010
2	Small Interfering RNA (siRNA)IBA 05/2012 - 07/2010
2	Interleukin-17 (Interleukin 17)IBA 03/2009 - 12/2008
2	Interleukin-12 (IL 12)IBA 03/2007 - 01/2007
1	NeuropilinsIBA 04/2022
1	CalcineurinIBA 01/2022
1	Angiotensin IIIBA 01/2022
1	ActomyosinIBA 01/2022
1	Metalloproteases (Metalloproteinases)IBA 01/2022
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2022
1	cysteine and glycine-rich protein 3IBA 01/2022
1	InflammasomesIBA 11/2021
1	CholesterolIBA 11/2021
1	DesmosterolIBA 11/2021
1	SterolsIBA 11/2021
1	Histone-Lysine N-MethyltransferaseIBA 01/2021
1	Histones (Histone)IBA 01/2021
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021
1	A-factor (Streptomyces)IBA 11/2020
1	AntibodiesIBA 11/2020
1	Blood Group Antigens (Blood Groups)IBA 04/2020
1	ABO Blood-Group SystemIBA 04/2020
1	1,3,4,6- tetra- O- acetyl- 2- azido- 2- deoxyglucopyranose (TAAD)IBA 01/2020

Therapy/Procedure

8	Transplantation 01/2021 - 01/2004
7	Therapeutics 01/2022 - 03/2007
3	Heart Transplantation (Grafting, Heart) 11/2015 - 03/2007
2	Renal Dialysis (Hemodialysis) 01/2022 - 07/2021
2	Organ Transplantation 08/2012 - 09/2008
1	Bioreactors (Bioreactor) 01/2021